Games likeSubstrate: Emergence
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ObscureGridworld
53% matchGod Game, Science, Similar premise
ObscureSwarmdustry
47% matchColony Sim, Crafting, Similar premise
ObscureCellings
48% matchGod Game, Creature Collector
ObscureEvoLife
50% matchGod Game, Science, Similar premise
ObscureGelluloid Domination
42% matchScience, RTS, Similar premise
ObscureTerritory: Animals Genetic Strategy
49% matchGod Game, Colony Sim, Similar premise
ObscureVilmonic
49% matchGod Game, Science
AAPlanetary Life
53% matchGod Game, Science, Similar premise
ObscureLifecraft
49% matchGod Game, Science, Similar premise
ObscureParametric Creature: Lab
46% matchScience, Sandbox, Similar premise
ObscureLifeforms: Binary Fission
47% matchGod Game, Science, Similar premise
ObscureANLIFE: Motion-Learning Life Evolution
53% matchGod Game, Colony Sim, Similar premise
AAEcosystem
50% matchGod Game, Colony Sim, Similar premise
AAThrive
47% matchScience, Artificial Intelligence, Similar premise
ObscureBugLab Simulator
44% matchColony Sim, Creature Collector, Similar premise
ObscureEugenics
32% match
ObscureCreatura
48% matchScience, God Game, Similar premise
ObscureNature Game System
38% matchScience, Nature, Similar premise
ObscureDivinity Vassals
36% matchCreature Collector, RTS, accessibility options
ObscureStarShip-DF
44% matchColony Sim, God Game
ObscureEvolo.Evolution
43% matchGod Game, Sandbox
ObscureHere Comes The Swarm
40% matchColony Sim, RTS, accessibility options
ObscureBeetle Uprising
48% matchGod Game, Colony Sim
AAASPORE™
46% matchGod Game, Colony Sim
IndieCrafting Idle Clicker
37% matchOften compared to it, Sandbox, Management
ObscureGenome Guardian 2
36% matchScience, Roguelite, Similar premise
Obscuresoul Interface
39% matchGod Game, Colony Sim
ObscurePHYSARUM: Slime Mold Simulator
43% matchScience, God Game
ObscureTradingLife
31% matchStrategy, Simulation, accessibility options
IndieGame Dev Studio
38% matchOften compared to it, Management, Simulation
ObscureCreature Creation Station
42% matchGod Game, Creature Collector
ObscureIntelligent Design: An Evolutionary Sandbox
44% matchGod Game, Science
AAMonster Lab Simulator
39% matchScience, Creature Collector
ObscureFungal Colony Sim 2
36% matchGod Game, Procedural Generation, Similar premise
ObscureULTRAFUN
38% matchColony Sim, Creature Collector
Obscureatomica
33% matchScience, Exploration
ObscureMycelium Conquest
39% matchSandbox, Procedural Generation, Similar premise
ObscureAmoeba Battle: Microscopic RTS Action
31% matchRTS, Roguelite, Similar premise
ObscureHeliotropism
34% matchSandbox, Nature, Similar premise
ObscureGrowth
34% matchProcedural Generation, Strategy, Similar premise
IndieSpecies: Artificial Life, Real Evolution
42% matchGod Game, Science, Similar premise
AAVoxel Tycoon
35% matchOften compared to it, Sandbox, Crafting
ObscureGalaxy Too Far
39% matchGod Game, Artificial Intelligence
ObscureDon't get lost
37% matchColony Sim, Sandbox
IndieThe Sapling
43% matchGod Game, Science
ObscureMulticellular
37% matchScience, Nature
ObscureCreature Lab
32% matchCreature Collector, Sandbox
ObscureMicro Solar Punk
33% matchRTS, Procedural Generation